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Lack of glutathione peroxidase-1 exacerbates a beta-mediated neurotoxicity in cortical neurons

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( Figures 5A, B ) Compared to cells treated with CB-839, venetoclax and AZD-5991 treated cells exhibited greater suppression of mitochondrial respiration

Ferroptosis in the liver microenvironment Glucose metabolism: a dynamic regulator of iron homeostasis Iron homeostasis is maintained by balancing iron supply with iron loss, erythropoiesis being a major part of iron demand, while iron supply arises primarily from intestinal absorption and iron cycling in macrophages [139, 140]